Mouse Rcvrn Antibody

ProSci
Product Code: PSI-60-455
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-60-455-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstratesdetected the Rcvrn protein (arrow).

Western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstratesdetected the Rcvrn protein (arrow).

Further Information

Additional Names:
Recoverin, 23 kDa photoreceptor cell-specific protein, Cancer-associated retinopathy protein, Protein CAR, Rcvrn, Rcv1
Application Note:
For WB starting dilution is: 1:1000
Background:
Rcvrn seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.
Background References:
  • Jin, K., et al. J. Neurosci. 30(36):11902-11916(2010)
  • Georgi, S.A., et al. J. Neurosci. 30(11):4048-4061(2010)
  • Sanuki, R., et al. FEBS Lett. 584(4):753-758(2010)
  • Brzezinski, J.A. IV, et al. Development 137(4):619-629(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Rcvrn antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-67 amino acids from the N-terminal region of mouse Rcvrn.
NCBI Gene ID #:
19674
NCBI Official Name:
Recoverin
NCBI Official Symbol:
Rcvrn
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
P34057
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
P34057
User NOte:
Optimal dilutions for each application to be determined by the researcher.