CRYM Antibody
| Code | Size | Price |
|---|
| PSI-60-710-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ketimine reductase mu-crystallin, NADP-regulated thyroid-hormone-binding protein, CRYM, THBP
Application Note:
For WB starting dilution is: 1:1000
Background:
Crystallins are separated into two classes: taxon-specific
and ubiquitous. The former class is also called
phylogenetically-restricted crystallins. The latter class
constitutes the major proteins of vertebrate eye lens and maintains
the transparency and refractive index of the lens. This gene
encodes a taxon-specific crystallin protein that binds NADPH and
has sequence similarity to bacterial ornithine cyclodeaminases. The
encoded protein does not perform a structural role in lens tissue,
and instead it binds thyroid hormone for possible regulatory or
developmental roles. Mutations in this gene have been associated
with autosomal dominant non-syndromic deafness. Multiple
alternatively spliced transcript variants have been found for this
gene.
Background References:
- Martins-de-Souza, D., et al.Psychiatr Res (2010) In press :
- Al-Kafaji, G., et al. Biochem. Biophys. Res. Commun. 391(4):1585-1591(2010)
- Malinowska, K., et al. Prostate 69(10):1109-1118(2009)
- Martins-de-Souza, D., et al.Psychiatr Res 43(11):978-986(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CRYM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the Central region of human CRYM.
NCBI Gene ID #:
1428
NCBI Official Name:
Ketimine reductase mu-crystallin
NCBI Official Symbol:
CRYM
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
Q14894
Protein GI Number:
2498259
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q14894
User NOte:
Optimal dilutions for each application to be determined by the researcher.