CPLX1 Antibody
Code | Size | Price |
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PSI-63-934-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Complexin-1, Complexin I, CPX I, Synaphin-2, CPLX1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
CPLX1 encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release.
Background References:
- Salimi, K., et al. Synapse 62(4):273-282(2008)
- Giraudo, C.G., et al. Science 313(5787):676-680(2006)
- Kishi, T., et al. Schizophr. Res. 82 (2-3), 185-189 (2006) :
- Basso, M., et al. Proteomics 4(12):3943-3952(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Rat
Immunogen:
This CPLX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-60 amino acids from the Central region of human CPLX1.
NCBI Gene ID #:
10815
NCBI Official Name:
Complexin-1
NCBI Official Symbol:
CPLX1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
15 kDa
Protein Accession #:
O14810
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
O14810
User NOte:
Optimal dilutions for each application to be determined by the researcher.