COX5A Antibody
| Code | Size | Price |
|---|
| PSI-56-887-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cytochrome c oxidase subunit 5A, mitochondrial, Cytochrome c oxidase polypeptide Va, COX5A
Application Note:
For WB starting dilution is: 1:1000
Background:
Cytochrome c oxidase (COX) is the terminal enzyme of the
mitochondrial respiratory chain. It is a multi-subunit enzyme
complex that couples the transfer of electrons from cytochrome c to
molecular oxygen and contributes to a proton electrochemical
gradient across the inner mitochondrial membrane. The complex
consists of 13 mitochondrial- and nuclear-encoded subunits. The
mitochondrially-encoded subunits perform the electron transfer of
proton pumping activities. The functions of the nuclear-encoded
subunits are unknown but they may play a role in the regulation and
assembly of the complex. This gene encodes the nuclear-encoded
subunit Va of the human mitochondrial respiratory chain enzyme. A
pseudogene COX5AP1 has been found in chromosome 14q22. [provided by
RefSeq].
Background References:
- Chen, Z.X., et al. Cell Death Differ. 17(3):408-420(2010)
- Fornuskova, D., et al. Biochem. J. 428(3):363-374(2010)
- Uddin, M., et al. BMC Evol. Biol. 8,(2008) :
- Williams, S.L., et al. J. Biol. Chem. 279(9):7462-7469(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This COX5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human COX5A.
NCBI Gene ID #:
9377
NCBI Official Name:
Cytochrome c oxidase subunit 5A, mitochondrial
NCBI Official Symbol:
COX5A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
17 kDa
Protein Accession #:
P20674
Protein GI Number:
218511986
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity
Swissprot #:
P20674
User NOte:
Optimal dilutions for each application to be determined by the researcher.