XYLT2 Antibody
| Code | Size | Price |
|---|
| PSI-60-352-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Xylosyltransferase 2, Peptide O-xylosyltransferase 1, Xylosyltransferase II, XT-II, XylT-II, XYLT2, XT2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is an isoform of
xylosyltransferase, which belongs to a family of
glycosyltransferases. This enzyme transfers xylose from UDP-xylose
to specific serine residues of the core protein and initiates the
biosynthesis of glycosaminoglycan chains in proteoglycans including
chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate.
The enzyme activity, which is increased in scleroderma patients, is
a diagnostic marker for the determination of sclerotic activity in
systemic sclerosis.
Background References:
- Condac, E., et al. Glycobiology 19(8):829-833(2009)
- Casanova, J.C., et al. Biochem. Biophys. Res. Commun. 383(1):4-10(2009)
- Ponighaus, C., et al. Am. J. Hypertens. 22(4):432-436(2009)
- Ambrosius, M., et al. Clin. Biochem. 42 (1-2), 1-4 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This XYLT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human XYLT2.
NCBI Gene ID #:
64132
NCBI Official Name:
Xylosyltransferase 2
NCBI Official Symbol:
XYLT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
97 kDa
Protein Accession #:
Q9H1B5
Protein GI Number:
126302616
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9H1B5
User NOte:
Optimal dilutions for each application to be determined by the researcher.