PKD2 Antibody
| Code | Size | Price |
|---|
| PSI-58-019-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Polycystin-2, Autosomal dominant polycystic kidney disease type II protein, Polycystic kidney disease 2 protein, Polycystwin, R48321, PKD2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the polycystin protein
family. The encoded protein contains multiple transmembrane
domains, and cytoplasmic N- and C-termini. The protein may be an
integral membrane protein involved in cell-cell/matrix
interactions. The encoded protein may function in renal tubular
development, morphology, and function, and may modulate
intracellular calcium homoeostasis and other signal transduction
pathways. This protein interacts with polycystin 1 to produce
cation-permeable currents. Mutations in this gene have been
associated with autosomal dominant polycystic kidney disease.
Background References:
- Duning, K., et al. J. Biol. Chem. 285(44):33584-33588(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Stewart, A.P., et al. Biophys. J. 99(3):790-797(2010)
- Petri, E.T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(20):9176-9181(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PKD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 874-903 amino acids from the C-terminal region of human PKD2.
NCBI Gene ID #:
5311
NCBI Official Name:
Polycystin-2
NCBI Official Symbol:
PKD2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
110 kDa
Protein Accession #:
Q13563
Protein GI Number:
116242717
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q13563
User NOte:
Optimal dilutions for each application to be determined by the researcher.