ALDH8A1 Antibody

ProSci
Product Code: PSI-57-997
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-997-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:2000 dilution + mouse liver lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:2000 dilution + mouse liver lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Aldehyde dehydrogenase family 8 member A1, 121-, Aldehyde dehydrogenase 12, ALDH8A1, ALDH12
Application Note:
For WB starting dilution is: 1:2000
Background:
ALDH8A1 belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal.
Background References:
  • Lin,M.,J. Biol. Chem. 275 (51), 40106-40112 (2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ALDH8A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-416 amino acids from the C-terminal region of human ALDH8A1.
NCBI Gene ID #:
64577
NCBI Official Name:
Aldehyde dehydrogenase family 8 member A1
NCBI Official Symbol:
ALDH8A1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
Q9H2A2
Protein GI Number:
74752601
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9H2A2
User NOte:
Optimal dilutions for each application to be determined by the researcher.