PTPN14 Antibody
| Code | Size | Price |
|---|
| PSI-58-009-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tyrosine-protein phosphatase non-receptor type 14, Protein-tyrosine phosphatase pez, PTPN14, PEZ, PTPD2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the
protein tyrosine phosphatase (PTP) family. PTPs are known to be
signaling molecules that regulate a variety of cellular processes
including cell growth, differentiation, mitotic cycle, and
oncogenic transformation. This PTP contains an N-terminal
noncatalytic domain similar to that of band 4.1 superfamily
cytoskeleton-associated proteins, which suggested the membrane or
cytoskeleton localization of this protein. It appears to regulate
lymphatic development in mammals, and a loss of function mutation
has been found in a kindred with a lymphedema-choanal atresia.
Background References:
- Au, A.C., et al. Am. J. Hum. Genet. 87(3):436-444(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Wyatt, L., et al. Cell Cycle 7(15):2290-2295(2008)
- Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PTPN14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 862-890 amino acids from the C-terminal region of human PTPN14.
NCBI Gene ID #:
5784
NCBI Official Name:
Tyrosine-protein phosphatase non-receptor type 14
NCBI Official Symbol:
PTPN14
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
135 kDa
Protein Accession #:
Q15678
Protein GI Number:
209572662
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q15678
User NOte:
Optimal dilutions for each application to be determined by the researcher.