PLCD3 Antibody
| Code | Size | Price |
|---|
| PSI-57-887-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3, Phosphoinositide phospholipase C-delta-3, Phospholipase C-delta-3, PLC-delta-3, PLCD3, KIAA1964
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the phospholipase C family,
which catalyze the hydrolysis of phosphatidylinositol
4,5-bisphosphate to generate the second messengers diacylglycerol
and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3
mediate a variety of cellular responses to extracellular stimuli by
inducing protein kinase C and increasing cytosolic Ca(2+)
concentrations. This enzyme localizes to the plasma membrane and
requires calcium for activation. Its activity is inhibited by
spermine, sphingosine, and several phospholipids. [provided by
RefSeq].
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Segat, L., et al. Vaccine 28(10):2201-2206(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Newton-Cheh, C., et al. Nat. Genet. 41(6):666-676(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PLCD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human PLCD3.
NCBI Gene ID #:
113026
NCBI Official Name:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
NCBI Official Symbol:
PLCD3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
89 kDa
Protein Accession #:
Q8N3E9
Protein GI Number:
158706388
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8N3E9
User NOte:
Optimal dilutions for each application to be determined by the researcher.