Mouse Ksr1 Antibody

ProSci
Product Code: PSI-57-513
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-513-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).

Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).

Further Information

Additional Names:
Kinase suppressor of Ras 1, mKSR1, Protein Hb, Ksr1, Ksr
Application Note:
For WB starting dilution is: 1:1000
Background:
Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.
Background References:
  • Costanzo-Garvey, D.L., et al. Cell Metab. 10(5):366-378(2009)
  • McKay, M.M., et al. Proc. Natl. Acad. Sci. U.S.A. 106(27):11022-11027(2009)
  • Razidlo, G.L., et al. J. Biol. Chem. 284(11):6705-6715(2009)
  • Giurisato, E., et al. Mol. Cell. Biol. 29(6):1554-1564(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Ksr1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 719-747 amino acids from the C-terminal region of mouse Ksr1.
NCBI Gene ID #:
16706
NCBI Official Name:
Kinase suppressor of Ras 1
NCBI Official Symbol:
Ksr1
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
97 kDa
Protein Accession #:
Q61097
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q61097
User NOte:
Optimal dilutions for each application to be determined by the researcher.