PPP1R1C Antibody

ProSci
Product Code: PSI-60-075
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-075-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse liver tissue lysates (35ug/lane).

Western blot analysis in mouse liver tissue lysates (35ug/lane).

Further Information

Additional Names:
Protein phosphatase 1 regulatory subunit 1C, Inhibitor-5 of protein phosphatase 1, IPP5, PPP1R1C
Application Note:
For WB starting dilution is: 1:1000
Background:
Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]).[supplied by OMIM].
Background References:
  • Dick, D.M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. (2010) In press :
  • Rose, J. Phd, et al. Mol. Med. (2010) In press :
  • Zeng, Q., et al. Biotechnol. Appl. Biochem. 54(4):231-238(2009)
  • Wang, X., et al. J. Biol. Chem. 283(18):12076-12084(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PPP1R1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-76 amino acids from the N-terminal region of human PPP1R1C.
NCBI Gene ID #:
151242
NCBI Official Name:
Protein phosphatase 1 regulatory subunit 1C
NCBI Official Symbol:
PPP1R1C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
12 kDa
Protein Accession #:
Q8WVI7
Protein GI Number:
74730857
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8WVI7
User NOte:
Optimal dilutions for each application to be determined by the researcher.