TBCC Antibody
| Code | Size | Price |
|---|
| PSI-57-065-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tubulin-specific chaperone C, Tubulin-folding cofactor C, CFC, TBCC
Application Note:
For WB starting dilution is: 1:1000
Background:
Cofactor C is one of four proteins (cofactors A, D, E, and
C) involved in the pathway leading to correctly folded beta-tubulin
from folding intermediates. Cofactors A and D are believed to play
a role in capturing and stabilizing beta-tubulin intermediates in a
quasi-native confirmation. Cofactor E binds to the cofactor
D/beta-tubulin complex; interaction with cofactor C then causes the
release of beta-tubulin polypeptides that are committed to the
native state.
Background References:
- Hage-Sleiman, R., et al. BMC Cancer 10, 135 (2010) :
- Nature 447(7145):661-678(2007)
- Mungall, A.J., et al. Nature 425(6960):805-811(2003)
- Bartolini, F., et al. J. Biol. Chem. 277(17):14629-14634(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TBCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human TBCC.
NCBI Gene ID #:
6903
NCBI Official Name:
Tubulin-specific chaperone C
NCBI Official Symbol:
TBCC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q15814
Protein GI Number:
313104020
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q15814
User NOte:
Optimal dilutions for each application to be determined by the researcher.