Mouse Ltk Antibody
Code | Size | Price |
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PSI-57-515-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Leukocyte tyrosine kinase receptor, Ltk
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the
ros/insulin receptor family of tyrosine kinases. Tyrosine-specific
phosphorylation of proteins is a key to the control of diverse
pathways leading to cell growth and differentiation. Four
alternatively spliced transcript variants encoding different
isoforms have been described for this gene. These transcripts are
expressed in a tissue-specific manner in lymphocytes, brain and
neuroblastoma cells, and the encoded isoforms exhibit different
subcellular localization. The lymphocyte and brain specific
variants initiate translation at non-AUG (CUG) start codons.
Background References:
- Li, J., et al. J. Biol. Chem. 283(49):34260-34272(2008)
- Yu, X., et al. J. Immunol. 177(10):7042-7049(2006)
- Li, N., et al. Hum. Mol. Genet. 13(2):171-179(2004)
- Thut, C.J., et al. Dev. Biol. 231(1):63-76(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Ltk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 795-822 amino acids from the C-terminal region of mouse Ltk.
NCBI Gene ID #:
17005
NCBI Official Name:
Leukocyte tyrosine kinase receptor
NCBI Official Symbol:
Ltk
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
94 kDa
Protein Accession #:
P08923
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P08923
User NOte:
Optimal dilutions for each application to be determined by the researcher.