Mouse Ltk Antibody

ProSci
Product Code: PSI-57-515
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-515-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstratedetected the Ltk protein (arrow).

Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstratedetected the Ltk protein (arrow).

Further Information

Additional Names:
Leukocyte tyrosine kinase receptor, Ltk
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Four alternatively spliced transcript variants encoding different isoforms have been described for this gene. These transcripts are expressed in a tissue-specific manner in lymphocytes, brain and neuroblastoma cells, and the encoded isoforms exhibit different subcellular localization. The lymphocyte and brain specific variants initiate translation at non-AUG (CUG) start codons.
Background References:
  • Li, J., et al. J. Biol. Chem. 283(49):34260-34272(2008)
  • Yu, X., et al. J. Immunol. 177(10):7042-7049(2006)
  • Li, N., et al. Hum. Mol. Genet. 13(2):171-179(2004)
  • Thut, C.J., et al. Dev. Biol. 231(1):63-76(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Ltk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 795-822 amino acids from the C-terminal region of mouse Ltk.
NCBI Gene ID #:
17005
NCBI Official Name:
Leukocyte tyrosine kinase receptor
NCBI Official Symbol:
Ltk
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
94 kDa
Protein Accession #:
P08923
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P08923
User NOte:
Optimal dilutions for each application to be determined by the researcher.