POF1B Antibody
| Code | Size | Price |
|---|
| PSI-57-299-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein POF1B, Premature ovarian failure protein 1B, POF1B
Application Note:
For WB starting dilution is: 1:1000
Background:
Premature ovarian failure (POF) is characterized by
primary or secondary amenorrhea in women less than 40 years old.
Two POF susceptibility regions called 'POF1' and 'POF2' have been
identified by breakpoint mapping of X-autosome translocations. POF1
extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1.
This gene, POF1B, resides in the POF2 region. This gene is
expressed at trace levels in mouse prenatal ovary and is barely
detectable or absent from adult ovary, in human and in the mouse
respectively. This gene's expression is restricted to epithelia
with its highest expression in the epidermis, and oro-pharyngeal
and gastro-intestinal tracts. The protein encoded by this gene
binds non-muscle actin filaments. The role this gene may play in
the etiology of premature ovarian failure remains to be determined.
Background References:
- Rizzolio, F., et al. Gene Expr. Patterns 7(4):529-534(2007)
- Lacombe, A., et al. Am. J. Hum. Genet. 79(1):113-119(2006)
- Bione, S., et al. Hum. Reprod. 19(12):2759-2766(2004)
- Bione, S., et al. Semin. Reprod. Med. 18(1):51-57(2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This POF1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the Central region of human POF1B.
NCBI Gene ID #:
79983
NCBI Official Name:
Protein POF1B
NCBI Official Symbol:
POF1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
Q8WVV4
Protein GI Number:
332278224
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8WVV4
User NOte:
Optimal dilutions for each application to be determined by the researcher.