SEC31A Antibody

ProSci
Product Code: PSI-60-905
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-60-905-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse lung tissue lysates (35ug/lane).

Western blot analysis in mouse lung tissue lysates (35ug/lane).

Further Information

Additional Names:
Protein transport protein Sec31A, ABP125, ABP130, SEC31-like protein 1, SEC31-related protein A, Web1-like protein, SEC31A, KIAA0905, SEC31L1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII , in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
Background References:
  • Rose, J. Phd, et al. Mol. Med. (2010) In press :
  • Townley, A.K., et al. J. Cell. Sci. 121 (PT 18), 3025-3034 (2008) :
  • Stagg, S.M., et al. Cell 134(3):474-484(2008)
  • Shibata, H., et al. J. Biol. Chem. 283(15):9623-9632(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SEC31A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-502 amino acids from the Central region of human SEC31A.
NCBI Gene ID #:
22872
NCBI Official Name:
Protein transport protein Sec31A
NCBI Official Symbol:
SEC31A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
133 kDa
Protein Accession #:
O94979
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O94979
User NOte:
Optimal dilutions for each application to be determined by the researcher.