TIAM2 Antibody

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ProSci
Product Code: PSI-57-155
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-155-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

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Western blot analysis in mouse liver tissue lysates (35ug/lane).
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Western blot analysis in mouse liver tissue lysates (35ug/lane).

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Further Information

Additional Names:
T-lymphoma invasion and metastasis-inducing protein 2, TIAM-2, SIF and TIAM1-like exchange factor, TIAM2, KIAA2016, STEF
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described.
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003) :
  • Salehi, A.H., et al. J. Biol. Chem. 277(50):48043-48050(2002)
  • Yoshizawa, M., et al. Mech. Dev. 113(1):65-68(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TIAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 357-385 amino acids from the N-terminal region of human TIAM2.
NCBI Gene ID #:
26230
NCBI Official Name:
T-lymphoma invasion and metastasis-inducing protein 2
NCBI Official Symbol:
TIAM2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
190 kDa
Protein Accession #:
Q8IVF5
Protein GI Number:
296453025
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8IVF5
User NOte:
Optimal dilutions for each application to be determined by the researcher.