PTPRG Antibody
Code | Size | Price |
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PSI-58-007-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Receptor-type tyrosine-protein phosphatase gamma, Protein-tyrosine phosphatase gamma, R-PTP-gamma, PTPRG, PTPG
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the
protein tyrosine phosphatase (PTP) family. PTPs are known to be
signaling molecules that regulate a variety of cellular processes
including cell growth, differentiation, mitotic cycle, and
oncogenic transformation. This PTP possesses an extracellular
region, a single transmembrane region, and two tandem
intracytoplasmic catalytic domains, and thus represents a
receptor-type PTP. The extracellular region of this PTP contains a
carbonic anhydrase-like (CAH) domain, which is also found in the
extracellular region of PTPRBETA/ZETA. This gene is located in a
chromosomal region that is frequently deleted in renal cell
carcinoma and lung carcinoma, thus is thought to be a candidate
tumor suppressor gene.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Shu, S.T., et al. Anticancer Res. 30(6):1937-1946(2010)
- Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
- Bouyain, S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(6):2443-2448(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PTPRG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 671-700 amino acids from the Central region of human PTPRG.
NCBI Gene ID #:
5793
NCBI Official Name:
Receptor-type tyrosine-protein phosphatase gamma
NCBI Official Symbol:
PTPRG
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
162 kDa
Protein Accession #:
P23470
Protein GI Number:
229463033
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P23470
User NOte:
Optimal dilutions for each application to be determined by the researcher.