Mouse Sik2 Antibody
| Code | Size | Price |
|---|
| PSI-59-204-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Serine/threonine-protein kinase SIK2, Salt-inducible kinase 2, SIK-2, Serine/threonine-protein kinase SNF1-like kinase 2, Sik2, Snf1lk2
Application Note:
For WB starting dilution is: 1:1000
Background:
Phosphorylates 'Ser-789' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.
Background References:
- Trivedi, C.M., et al. Dev. Cell 19(3):450-459(2010)
- Muraoka, M., et al. Am. J. Physiol. Endocrinol. Metab. 296 (6), E1430-E1439 (2009) :
- Du, J., et al. Obesity (Silver Spring) 16(3):531-538(2008)
- Katoh, Y., et al. FEBS J. 273(12):2730-2748(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Sik2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 606-633 amino acids from the Central region of mouse Sik2.
NCBI Gene ID #:
235344
NCBI Official Name:
Serine/threonine-protein kinase SIK2
NCBI Official Symbol:
Sik2
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
104 kDa
Protein Accession #:
Q8CFH6
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8CFH6
User NOte:
Optimal dilutions for each application to be determined by the researcher.