Mouse Mknk2 Antibody
| Code | Size | Price |
|---|
| PSI-57-352-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
MAP kinase-interacting serine/threonine-protein kinase 2, MAP kinase signal-integrating kinase 2, MAPK signal-integrating kinase 2, Mnk2, Mknk2, Mnk2
Application Note:
For WB starting dilution is: 1:1000
Background:
Mknk2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity).
Background References:
- Ueda, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(32):13984-13990(2010)
- Furic, L., et al. Proc. Natl. Acad. Sci. U.S.A. 107(32):14134-14139(2010)
- Joshi, S., et al. Proc. Natl. Acad. Sci. U.S.A. 106(29):12097-12102(2009)
- Chrestensen, C.A., et al. Genes Cells 12(10):1133-1140(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This Mouse Mknk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of mouse Mknk2.
NCBI Gene ID #:
17347
NCBI Official Name:
MAP kinase-interacting serine/threonine-protein kinase 2
NCBI Official Symbol:
Mknk2
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
Q8CDB0
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8CDB0
User NOte:
Optimal dilutions for each application to be determined by the researcher.