NXT1 Antibody
| Code | Size | Price |
|---|
| PSI-60-697-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
NTF2-related export protein 1, Protein p15, NXT1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is located in the nuclear
envelope. It has protein similarity to nuclear transport factor 2.
This protein functions as a nuclear export factor in both RAN
(Ras-related nuclear protein)- and CRM1 (required for chromosome
region maintenance)-dependent pathways. It is found to stimulate
the export of U1 snRNA in RAN- and CRM1-dependent pathways and the
export of tRNA and mRNA in a CRM1-independent pathway. The encoded
protein heterodimerizes with Tap protein and may regulate the
ability of Tap protein to mediate nuclear mRNA export. The use of
alternate polyadenylation sites has been found for this gene.
Background References:
- Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
- Forler, D., et al. Nat. Biotechnol. 21(1):89-92(2003)
- Katahira, J., et al. J. Biol. Chem. 277(11):9242-9246(2002)
- Wiegand, H.L., et al. Mol. Cell. Biol. 22(1):245-256(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This NXT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-111 amino acids from the C-terminal region of human NXT1.
NCBI Gene ID #:
29107
NCBI Official Name:
NTF2-related export protein 1
NCBI Official Symbol:
NXT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
16 kDa
Protein Accession #:
Q9UKK6
Protein GI Number:
18203504
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9UKK6
User NOte:
Optimal dilutions for each application to be determined by the researcher.