Mouse Map4k2 Antibody

ProSci
Product Code: PSI-58-135
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-135-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse heart tissue lysates (35ug/lane).

Western blot analysis in mouse heart tissue lysates (35ug/lane).

Further Information

Additional Names:
Mitogen-activated protein kinase kinase kinase kinase 2, Germinal center kinase, GCK, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, MEKKK 2, Rab8-interacting protein, Map4k2, Rab8ip
Application Note:
For WB starting dilution is: 1:1000
Background:
Enhances MAP3K1 oligomerization, which may relieve amino-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. May play a role in the regulation of vesicle targeting or fusion.
Background References:
  • Zhong, J., et al. Proc. Natl. Acad. Sci. U.S.A. 106(11):4372-4377(2009)
  • Ren, M., et al. Proc. Natl. Acad. Sci. U.S.A. 93(10):5151-5155(1996)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Map4k2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 432-459 amino acids from the Central region of mouse Map4k2.
NCBI Gene ID #:
26412
NCBI Official Name:
Mitogen-activated protein kinase kinase kinase kinase 2
NCBI Official Symbol:
Map4k2
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
91 kDa
Protein Accession #:
Q61161
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q61161
User NOte:
Optimal dilutions for each application to be determined by the researcher.