Mouse Npr1 Antibody

ProSci
Product Code: PSI-57-461
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-461-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse heart tissue lysates (35ug/lane).
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Mouse Npr1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse duodenum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in mouse heart tissue lysates (35ug/lane).
Mouse Npr1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse duodenum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Atrial natriuretic peptide receptor 1, Atrial natriuretic peptide receptor type A, ANP-A, ANPR-A, NPR-A, Guanylate cyclase A, GC-A, Npr1, Npra
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
Background References:
  • Madhani, M., et al. Am. J. Physiol. Heart Circ. Physiol. 299 (3), H827-H836 (2010) :
  • Panayiotou, C.M., et al. Br. J. Pharmacol. 160(8):2045-2054(2010)
  • Ropero, A.B., et al. Endocrinology 151(8):3665-3674(2010)
  • Tankersley, C.G., et al. Inhal Toxicol 22(8):695-707(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Npr1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the N-terminal region of mouse Npr1.
NCBI Gene ID #:
18160
NCBI Official Name:
Atrial natriuretic peptide receptor 1
NCBI Official Symbol:
Npr1
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
119 kDa
Protein Accession #:
P18293
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P18293
User NOte:
Optimal dilutions for each application to be determined by the researcher.