Mouse Csnk1e Antibody
| Code | Size | Price |
|---|
| PSI-57-926-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Casein kinase I isoform epsilon, CKI-epsilon, CKIe, Csnk1e
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation.
Background References:
- Meng, Q.J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(34):15240-15245(2010)
- Sugiyama, Y., et al. Biochem. J. 427(3):489-497(2010)
- Etchegaray, J.P., et al. PLoS ONE(4), E10303 (2010) :
- Lee, H., et al. Proc. Natl. Acad. Sci. U.S.A. 106(50):21359-21364(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Human
Immunogen:
This Mouse Csnk1e antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-310 amino acids from the C-terminal region of mouse Csnk1e.
NCBI Gene ID #:
27373
NCBI Official Name:
Casein kinase I isoform epsilon
NCBI Official Symbol:
Csnk1e
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
Q9JMK2
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9JMK2
User NOte:
Optimal dilutions for each application to be determined by the researcher.