CBX8 Antibody
| Code | Size | Price |
|---|
| PSI-57-899-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Chromobox protein homolog 8, Polycomb 3 homolog, Pc3, hPc3, Rectachrome 1, CBX8, PC3, RC1
Application Note:
For WB starting dilution is: 1:1000
Background:
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Background References:
- Dietrich, N., et al. EMBO J. 26(6):1637-1648(2007)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Stelzl, U., et al. Cell 122(6):957-968(2005)
- Obuse, C., et al. Genes Cells 9(2):105-120(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CBX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the Central region of human CBX8.
NCBI Gene ID #:
57332
NCBI Official Name:
Chromobox protein homolog 8
NCBI Official Symbol:
CBX8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
Q9HC52
Protein GI Number:
78099843
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9HC52
User NOte:
Optimal dilutions for each application to be determined by the researcher.