TLE2 Antibody
| Code | Size | Price |
|---|
| PSI-56-312-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transducin-like enhancer protein 2, Enhancer of split groucho-like protein 2, ESG2, TLE2
Application Note:
For WB starting dilution is: 1:1000
Background:
TLE2 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
Background References:
- He, Z., et al. J. Virol. 84(4):2047-2062(2010)
- Arce, L., et al. BMC Cancer 9, 159 (2009) :
- Higa, L.A., et al. Nat. Cell Biol. 8(11):1277-1283(2006)
- Javed, A., et al. J. Cell. Sci. 113 (PT 12), 2221-2231 (2000) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TLE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 637-665 amino acids from the C-terminal region of human TLE2.
NCBI Gene ID #:
7089
NCBI Official Name:
Transducin-like enhancer protein 2
NCBI Official Symbol:
TLE2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
80 kDa
Protein Accession #:
Q04725
Protein GI Number:
20532416
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q04725
User NOte:
Optimal dilutions for each application to be determined by the researcher.