Mouse Khdrbs1 Antibody
Code | Size | Price |
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PSI-60-484-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
KH domain-containing, RNA-binding, signal transduction-associated protein 1, GAP-associated tyrosine phosphoprotein p62, Src-associated in mitosis 68 kDa protein, Sam68, p21 Ras GTPase-activating protein-associated p62, p68, Khdrbs1 {ECO:0000312|MGI:MGI:893579}
Application Note:
For WB starting dilution is: 1:1000
Background:
Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.
Background References:
- Sette, C., et al. J. Androl. 31(1):66-74(2010)
- Maroni, P., et al. Mol. Cell. Endocrinol. 309 (1-2), 26-31 (2009) :
- Paronetto, M.P., et al. J. Cell Biol. 185(2):235-249(2009)
- Huot, M.E., et al. Mol. Cell. Biol. 29(7):1933-1943(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Human, Rat
Immunogen:
This Mouse Khdrbs1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-443 amino acids from the C-terminal region of mouse Khdrbs1.
NCBI Gene ID #:
20218
NCBI Official Name:
KH domain-containing, RNA-binding, signal transduction-associated protein 1
NCBI Official Symbol:
Khdrbs1
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
Q60749
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q60749
User NOte:
Optimal dilutions for each application to be determined by the researcher.