ZNF238 Antibody
| Code | Size | Price |
|---|
| PSI-61-172-200ul | 200ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Zinc finger and BTB domain-containing protein 18, 58 kDa repressor protein, Transcriptional repressor RP58, Translin-associated zinc finger protein 1, TAZ-1, Zinc finger protein 238, Zinc finger protein C2H2-171, ZBTB18, RP58, TAZ1, ZNF238
Application Note:
For WB starting dilution is: 1:2000
Background:
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'- [AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus.
Background References:
- Becker K.G.,et al.Hum. Mol. Genet. 4:685-691(1995).
- Aoki K.,et al.J. Biol. Chem. 273:26698-26704(1998).
- Meng G.,et al.Gene 242:59-64(2000).
- Ota T.,et al.Nat. Genet. 36:40-45(2004).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This ZNF238 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 318-331 amino acids from human ZNF238.
NCBI Gene ID #:
10472
NCBI Official Name:
Zinc finger and BTB domain-containing protein 18
NCBI Official Symbol:
ZBTB18
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
Q99592
Protein GI Number:
20141020
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q99592
User NOte:
Optimal dilutions for each application to be determined by the researcher.