SP2 Antibody

ProSci
Product Code: PSI-56-861
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-861-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse lung tissue lysates (35ug/lane).

Western blot analysis in mouse lung tissue lysates (35ug/lane).

Further Information

Additional Names:
Transcription factor Sp2, SP2, KIAA0048
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.
Background References:
  • Ito, H., et al. Biochim. Biophys. Acta 1789 (11-12), 681-690 (2009) :
  • Wheeler, H.E., et al. PLoS Genet.(10), E1000685 (2009) :
  • Letourneur, M., et al. Mol. Immunol. 46 (11-12), 2151-2160 (2009) :
  • Sun, J.M., et al. J. Biol. Chem. 282(45):33227-33236(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-526 amino acids from the C-terminal region of human SP2.
NCBI Gene ID #:
6668
NCBI Official Name:
Transcription factor Sp2
NCBI Official Symbol:
SP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
Q02086
Protein GI Number:
119370531
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q02086
User NOte:
Optimal dilutions for each application to be determined by the researcher.