ETV6 Antibody
| Code | Size | Price |
|---|
| PSI-57-766-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transcription factor ETV6, ETS translocation variant 6, ETS-related protein Tel1, Tel, ETV6, TEL, TEL1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes an ETS family transcription factor. The
product of this gene contains two functional domains: a N-terminal
pointed (PNT) domain that is involved in protein-protein
interactions with itself and other proteins, and a C-terminal
DNA-binding domain. Gene knockout studies in mice suggest that it
is required for hematopoiesis and maintenance of the developing
vascular network. This gene is known to be involved in a large
number of chromosomal rearrangements associated with leukemia and
congenital fibrosarcoma.
Background References:
- Otsubo, K., et al. Cancer Genet. Cytogenet. 202(1):22-26(2010)
- Roukens, M.G., et al. Nat. Cell Biol. 12(10):933-942(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Gascon, E., et al. J. Neurosci. 30(37):12414-12423(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This ETV6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-202 amino acids from the Central region of human ETV6.
NCBI Gene ID #:
2120
NCBI Official Name:
Transcription factor ETV6
NCBI Official Symbol:
ETV6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
P41212
Protein GI Number:
730927
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P41212
User NOte:
Optimal dilutions for each application to be determined by the researcher.