HOXD13 Antibody

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ProSci
Product Code: PSI-55-716
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-55-716-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse bladder tissue lysates (35ug/lane).
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Western blot analysis in mouse bladder tissue lysates (35ug/lane).

Documents

Further Information

Additional Names:
Homeobox protein Hox-D13, Homeobox protein Hox-4I, HOXD13, HOX4I
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in this particular gene cause synpolydactyly.
Background References:
  • Sugie, Y., et al. Brain Dev. 32(5):356-361(2010)
  • Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
  • Salsi, V., et al. Mol. Cell. Biol. 29(21):5775-5788(2009)
  • Cantile, M., et al. Int. J. Cancer 125(7):1532-1541(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HOXD13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-230 amino acids from the Central region of human HOXD13.
NCBI Gene ID #:
3239
NCBI Official Name:
Homeobox protein Hox-D13
NCBI Official Symbol:
HOXD13
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa
Protein Accession #:
P35453
Protein GI Number:
223590221
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P35453
User NOte:
Optimal dilutions for each application to be determined by the researcher.