PRRX2 Antibody

ProSci
Product Code: PSI-60-703
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-703-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse liver tissue lysates (35ug/lane).

Western blot analysis in mouse liver tissue lysates (35ug/lane).

Further Information

Additional Names:
Paired mesoderm homeobox protein 2, Paired-related homeobox protein 2, PRX-2, PRRX2, PMX2, PRX2
Application Note:
For WB starting dilution is: 1:1000
Background:
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.
Background References:
  • Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
  • Eriksson, N., et al. PLoS Genet.(6), E1000993 (2010) :
  • Tokutomi, Y., et al. Biochem. Biophys. Res. Commun. 364(4):822-830(2007)
  • Wissmuller, S., et al. Nucleic Acids Res. 34(6):1735-1744(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PRRX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-250 amino acids from the C-terminal region of human PRRX2.
NCBI Gene ID #:
51450
NCBI Official Name:
Paired mesoderm homeobox protein 2
NCBI Official Symbol:
PRRX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
Q99811
Protein GI Number:
12644475
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q99811
User NOte:
Optimal dilutions for each application to be determined by the researcher.