B3GALT2 Antibody
| Code | Size | Price |
|---|
| PSI-57-764-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Beta-1,3-galactosyltransferase 2, Beta-1,3-GalTase 2, Beta3Gal-T2, Beta3GalT2, 241-, UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2, B3GALT2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the
beta-1,3-galactosyltransferase (beta3GalT) gene family. This family
encodes type II membrane-bound glycoproteins with diverse enzymatic
functions using different donor substrates (UDP-galactose and
UDP-N-acetylglucosamine) and different acceptor sugars
(N-acetylglucosamine, galactose, N-acetylgalactosamine). The
beta3GalT genes are distantly related to the Drosophila Brainiac
gene and have the protein coding sequence contained in a single
exon. The beta3GalT proteins also contain conserved sequences not
found in the beta4GalT or alpha3GalT proteins. The carbohydrate
chains synthesized by these enzymes are designated as type 1,
whereas beta4GalT enzymes synthesize type 2 carbohydrate chains.
The ratio of type 1:type 2 chains changes during embryogenesis. By
sequence similarity, the beta3GalT genes fall into at least two
groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3,
beta3GalT5). This gene encodes a protein that functions in N-linked
glycoprotein glycosylation and shows strict donor substrate
specificity for UDP-galactose.
Background References:
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
- Sood, R., et al. Genomics 73(2):211-222(2001)
- Amado, M., et al. Biochim. Biophys. Acta 1473(1):35-53(1999)
- Amado, M., et al. J. Biol. Chem. 273(21):12770-12778(1998)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This B3GALT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-422 amino acids from the C-terminal region of human B3GALT2.
NCBI Gene ID #:
8707
NCBI Official Name:
Beta-1,3-galactosyltransferase 2
NCBI Official Symbol:
B3GALT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
O43825
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O43825
User NOte:
Optimal dilutions for each application to be determined by the researcher.