ORC5L Antibody

ProSci
Product Code: PSI-56-853
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-853-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse brain tissue lysates (35ug/lane).

Western blot analysis in mouse brain tissue lysates (35ug/lane).

Further Information

Additional Names:
Origin recognition complex subunit 5, ORC5, ORC5L
Application Note:
For WB starting dilution is: 1:1000
Background:
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
Background References:
  • Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
  • Trynka, G., et al. Gut 58(8):1078-1083(2009)
  • Siddiqui, K., et al. J. Biol. Chem. 282(44):32370-32383(2007)
  • Clarke, C.A., et al. Biochem. J. 388 (PT 2), 705-712 (2005) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ORC5L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-256 amino acids from the Central region of human ORC5L.
NCBI Gene ID #:
5001
NCBI Official Name:
Origin recognition complex subunit 5
NCBI Official Symbol:
ORC5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
O43913
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O43913
User NOte:
Optimal dilutions for each application to be determined by the researcher.