HOXB6 Antibody

ProSci
Product Code: PSI-56-006
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-006-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse kidney tissue lysates (35ug/lane).
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HOXB6 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in mouse kidney tissue lysates (35ug/lane).
HOXB6 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Homeobox protein Hox-B6, Homeobox protein Hox-22, Homeobox protein Hox-2B, Homeobox protein Hu-2, HOXB6, HOX2B
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.
Background References:
  • Ferrai, C., et al. Mol. Biol. Cell 20(15):3543-3551(2009)
  • Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
  • Chen, T., et al. Eur. J. Hum. Genet. 15(1):23-28(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HOXB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the Central region of human HOXB6.
NCBI Gene ID #:
3216
NCBI Official Name:
Homeobox protein Hox-B6
NCBI Official Symbol:
HOXB6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
P17509
Protein GI Number:
116242515
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P17509
User NOte:
Optimal dilutions for each application to be determined by the researcher.