SLC11A2 Antibody
Code | Size | Price |
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PSI-57-280-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Natural resistance-associated macrophage protein 2, NRAMP 2, Divalent cation transporter 1, Divalent metal transporter 1, DMT-1, Solute carrier family 11 member 2, SLC11A2, DCT1, DMT1, NRAMP2
Application Note:
For WB starting dilution is: 1:2000
For IF starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Background:
This gene encodes a member of the solute carrier family 11
protein family. The product of this gene transports divalent metals
and is involved in iron absorption. Mutations in this gene are
associated with hypochromic microcytic anemia with iron overload. A
related solute carrier family 11 protein gene is located on
chromosome 2. Multiple transcript variants encoding different
isoforms have been found for this gene.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Tabuchi, M., et al. J. Cell. Sci. 123 (PT 5), 756-766 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SLC11A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-291 amino acids from the Central region of human SLC11A2.
NCBI Gene ID #:
4891
NCBI Official Name:
Natural resistance-associated macrophage protein 2
NCBI Official Symbol:
SLC11A2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
62 kDa
Protein Accession #:
P49281
Protein GI Number:
8247934
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P49281
User NOte:
Optimal dilutions for each application to be determined by the researcher.