HOXD10 Antibody
| Code | Size | Price |
|---|
| PSI-56-534-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Zebrafish
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Homeobox protein Hox-D10, Homeobox protein Hox-4D, Homeobox protein Hox-4E, HOXD10, HOX4D, HOX4E
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the Abd-B homeobox family and
encodes a protein with a homeobox DNA-binding domain. It is
included in a cluster of homeobox D genes located on chromosome 2.
The encoded nuclear protein functions as a sequence-specific
transcription factor that is expressed in the developing limb buds
and is involved in differentiation and limb development. Mutations
in this gene have been associated with Wilm's tumor and congenital
vertical talus (also known as 'rocker-bottom foot' deformity or
congenital convex pes valgus) and/or a foot deformity resembling
that seen in Charcot-Marie-Tooth disease.
Background References:
- Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
- Reddy, S.D., et al. Cancer Res. 68(20):8195-8200(2008)
- Gurnett, C.A., et al. Clin. Orthop. Relat. Res. 462, 27-31 (2007) :
- Zhao, X., et al. Am. J. Hum. Genet. 80(2):361-371(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken
Immunogen:
This HOXD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the C-terminal region of human HOXD10.
NCBI Gene ID #:
3236
NCBI Official Name:
Homeobox protein Hox-D10
NCBI Official Symbol:
HOXD10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
P28358
Protein GI Number:
143811403
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P28358
User NOte:
Optimal dilutions for each application to be determined by the researcher.