PCSK1 Antibody

ProSci
Product Code: PSI-61-337
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-337-200ul200ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Rat
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution + PC-12 whole cell lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:1000 dilution + PC-12 whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Neuroendocrine convertase 1, NEC 1, 3.4.21.93, Prohormone convertase 1, Proprotein convertase 1, PC1, PCSK1, NEC1
Application Note:
For WB starting dilution is: 1:1000
Background:
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin.
Background References:
  • Creemers J.W.M.,et al.FEBS Lett. 300:82-88(1992).
  • Seidah N.G.,et al.DNA Cell Biol. 11:283-289(1992).
  • Ohagi S.,et al.Diabetes 45:897-901(1996).
  • Ota T.,et al.Nat. Genet. 36:40-45(2004).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PCSK1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 175-207 amino acids from human PCSK1.
NCBI Gene ID #:
5122
NCBI Official Name:
Neuroendocrine convertase 1
NCBI Official Symbol:
PCSK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
84 kDa
Protein Accession #:
P29120
Protein GI Number:
116242674
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Obesity,Neuroscience,Signal Transduction
Swissprot #:
P29120
User NOte:
Optimal dilutions for each application to be determined by the researcher.