6,8-Difluoro-7-hydroxy-4-methylcumarin
| Code | Size | Price |
|---|
| CDX-D0059-M025 | 25 mg | £194.00 |
Quantity:
| CDX-D0059-M050 | 50 mg | £340.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20 °C
Documents
Further Information
Alternate Names/Synonyms:
DiFMU; Marina blue; 6,8-Difluoro-7-hydroxy-4-methyl-2H-1-benzopyran-2-one
Appearance:
White to off-white solid.
CAS:
215868-23-8
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.Protect from light and moisture.
InChi:
InChI=1S/C10H6F2O3/c1-4-2-7(13)15-10-5(4)3-6(11)9(14)8(10)12/h2-3,14H,1H3
InChiKey:
LLENVBUPWUQAGL-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 215868-23-8. Formula: C10H6F2O3. MW: 212.15. Synthetic. UV-excitable blue fluorescent blue dye. Used to label Abeta-proteins, bacteria, histone deacetylase, nucleic acids, peptides, proteins and sugar chains. Applied in studies amplifying/detecting nucleic acid sequences, analyzing peptides, sugar chains, detecting bacteria, as a substrate for measuring acyl protein thioesterase (APT1), alpha-amylase, aryl sulfatases, beta-galactosidases, guanidinobenzoatase, beta-lactamase, lipase, phosphatases, protein kinases and xylanase activity. Used in diagnosing/treating traumatic brain injury, treating amyloidogenic disease and as temperature sensor. Can be used as a reference standard for substrates derived from this blue-fluorescent dye (CDX-D0164). Spectral data: &lambda|ex=362, &lambda|em=464.
MDL:
MFCD01073675
Molecular Formula:
C10H6F2O3
Molecular Weight:
212.15
Package Type:
Vial
Product Description:
UV-excitable blue fluorescent blue dye. Used to label Abeta-proteins, bacteria, histone deacetylase, nucleic acids, peptides, proteins and sugar chains. Applied in studies amplifying/detecting nucleic acid sequences, analyzing peptides, sugar chains, detecting bacteria, as a substrate for measuring acyl protein thioesterase (APT1), alpha-amylase, aryl sulfatases, beta-galactosidases, guanidinobenzoatase, beta-lactamase, lipase, phosphatases, protein kinases and xylanase activity. Used in diagnosing/treating traumatic brain injury, treating amyloidogenic disease and as temperature sensor. Can be used as a reference standard for substrates derived from this blue-fluorescent dye (CDX-D0164). Spectral data: lambda|ex=362, lambda|em=464.
Purity:
>98% (HPLC)
SMILES:
FC1=C2C(C(C)=CC(O2)=O)=CC(F)=C1O
Solubility Chemicals:
Soluble in DMSO, DMF or methanol.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) W.-C. Sun, et al.; Bioorg. Med. Chem. Lett. 8, 3107 (1998) | (2) A. Pashkova, et al.; Anal. Chem. 76, 4550 (2004) | (3) V. Ahmed, et al.; Anal. Biochem. 340, 80 (2005) | (4) S.-H. Kang, et al.; Anal. Biochem. 360, 1 (2007) | (5) J. Szucs, et al.; Analyst 134, 1601 (2009) | (6) R.W. Sabnis; Handbook of Fluorescent Dyes and Probes (2015)
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