BTLA Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-831-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
BTLA,CD272
Application Note:
This recombinant protein can be used for E, WB. For research use only.
Background:
B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.
Background References:
- Watanabe N., et al., 2003, Nat. Immunol. 4:670-679.
- Gavrieli M., et al., 2003, Biochem. Biophys. Res. Commun. 312:1236-1243.
- Sedy J.R., et al., 2005, Nat. Immunol. 6:90-98.
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human HVEM, His Tag at 5 ug/mL (100 uL/well) can bind Human BTLA (31-150), Fc Tag with a linear range of 0.08-1.25 ug/mL.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
Fc Tag
NCBI Gene ID #:
151888
NCBI Official Name:
B and T lymphocyte attenuator
NCBI Official Symbol:
BTLA
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
40.4 kDa
Protein Accession #:
AAP44003
Purity:
>92% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
AAP44003