VEGF R3 Recombinant Protein

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ProSci
Product Code: PSI-96-961
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-96-961-0.1mg0.1mg£657.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

Documents

Further Information

Additional Names:
Flt-4,FLT4,LMPH1A,PCLFLT41,VEGFR3,VEGFR-3,FLT-4,FLT-41,FLT41,PCL
Application Note:
This recombinant protein can be used for E, WB. For research use only.
Background:
Vascular endothelial growth factor receptor 3 (VEGF R3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). VEGF R3 mediates lymphangiogenesis in response to VEGF-C and VEGF-D. VEGF R3 is widely expressed in the early embryo but becomes restricted to lymphatic endothelia at later stages of development. It is likely that VEGF R3 may be important for lymph angiogenesis.
Background References:
  • Stuttfeld E., et al., 2009, IUBMB Life, 61 (9): 915-922.
  • Zygmunt T., et al., 2011, Dev Cell, 21 (2): 301-314.
  • Herzog, B., et al., 2011, Molecular Biology of the Cell, 22 (15): 2766-2776.
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human VEGF-C, His Tag at 5 ug/mL (100 uL/well) can bind Human VEGF R3, Fc Tag with a linear range of 0.6-10 ng/mL.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
Fc Tag
NCBI Gene ID #:
2324
NCBI Official Name:
vascular endothelial growth factor receptor 3 isoform 2 precursor
NCBI Official Symbol:
VEGF R3
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
111.2 kDa
Protein Accession #:
NP_002011.2
Purity:
>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P35916