B7-H5 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-826-0.1mg | 0.1mg | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
B7-H5,SISP1,Gi24,VISTA
Application Note:
This recombinant protein can be used for E, WB. For research use only.
Background:
Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
Background References:
- Sakr M.A., et al., 2010, Cancer Sci. 101:2368-2374.
- Mayya V., et al ., 2009, Sci. Signal. 2:RA46-RA46.
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human VSIG8, His Tag at 10 ug/mL (100 uL/well) can bind Human B7-H5, Fc Tag with a linear range of 0.625-20 ug/mL.
Buffer:
PBS, pH7.4
Fusion Tag:
Fc Tag
NCBI Gene ID #:
64115
NCBI Official Name:
Chromosome 10 open reading frame 54
NCBI Official Symbol:
B7-H5
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
44.8 kDa
Protein Accession #:
AAH20568
Purity:
>95% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9H7M9-1