CD163 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-843-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
CD163,M130
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is also known as hemoglobin scavenger receptor, which is a scavenger receptor for the hemoglobin-haptoglobin complex. CD163 has also been shown to mark cells of monocyte/macrophage lineage. A soluble form of the receptor exists in plasma, commonly denoted sCD163. sCD163 is generated by ectodomain shedding of the membrane bound receptor. sCD163 is upregulated in a large range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gaucher's disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.
Background References:
- Law S.K.A., et al., 1993, Eur. J. Immunol. 23:2320-2325.
- Matsushita N., et al., 2002, Clin. Exp. Immunol. 130:156-161.
- Ritter M., et al., 2001, Eur. J. Immunol. 31:999-1009.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
9332
NCBI Official Name:
Scavenger receptor cysteine-rich type 1 protein M130
NCBI Official Symbol:
CD163
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
110.4 kDa
Protein Accession #:
Q86VB7
Purity:
>95% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q86VB7