IGFBP-7 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-891-0.05mg | 0.05mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
IBP7,IGFBP7
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Insulin-like growth factor-binding protein 7 (IGFBP7) is also known as IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, prostacyclin-stimulating factor and tumor-derived adhesion factor, which contains one Ig-like C2-type (immunoglobulin-like) domain, one IGFBP N-terminal domain and one Kazal-like domain. The major function of IGFBP7 is the regulation of availability of insulin-like growth factors (IGFs) in tissue as well as in modulating IGF binding to its receptors. IGFBP7 binds to IGF with high affinity except for IGF-I and IGF-II.IGFBP7 also stimulates cell adhesion. Furthermore, IGFBP7 is implicated in some cancers.
Background References:
- Yamauchi T., et al., 1994, Biochem. J. 303:591-598.
- Oh Y., et al., 1996, J. Biol. Chem. 271:30322-30325.
- Wilson E.M., et al., 2001, J. Clin. Endocrinol. Metab. 86:4504-4511.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
3490
NCBI Official Name:
insulin-like growth factor-binding protein 7 isoform 1 precursor
NCBI Official Symbol:
IGFBP-7
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
27 kDa
Protein Accession #:
NP_001544
Purity:
>95% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q16270-1