CD28 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-979-0.1mg | 0.1mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
CD28,Tp44
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
Background References:
- Evans E.J., et al., 2005, Nat. Immunol. 6:271-279.
- Mayya V., et al., 2009, Sci. Signal. 2:RA46-RA46.
- Wollscheid B., et al., 2009, Nat. Biotechnol. 27:378-386.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
12487
NCBI Official Name:
T-cell-specific surface glycoprotein CD28 precursor
NCBI Official Symbol:
CD28
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Predicted Molecular Weight:
16.9 kDa
Protein Accession #:
NP_031668.3
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P31041