CD3 epsilon Recombinant Protein
Code | Size | Price |
---|
PSI-96-981-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
FLJ18683,T3E,TCRE,CD3E,CD3-epsilon
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Background References:
- Gold DP, et al., 1986, Nature 321 (6068): 431?4.
- Clevers HC, et al., 1988, Proc. Natl. Acad. Sci. U.S.A. 85 (21): 8156?60.
- Gil J, et al., 2011, J Clin Invest, 121(10):3872-6.
- Lu X, et al.,2011, Hematology, 16(3):185-9.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
Fc Tag
NCBI Gene ID #:
12501
NCBI Official Name:
T-cell surface glycoprotein CD3 epsilon chain
NCBI Official Symbol:
CD3 epsilon
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Predicted Molecular Weight:
36 kDa
Protein Accession #:
P22646
Purity:
>95% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P22646