B7-H5 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-975-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
B7-H5,SISP1,Gi24,VISTA
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
Background References:
- Sakr M.A., et al., 2010, Cancer Sci., 101: 2368-2374.
- Mayya V., et al ., 2009, Sci. Signal., 2: RA46-RA46.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
74048
NCBI Official Name:
V-type immunoglobulin domain-containing suppressor of T-cell activation isoform 2 precursor
NCBI Official Symbol:
B7-H5
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Predicted Molecular Weight:
19.7kDa
Protein Accession #:
NP_001153044.1
Purity:
>95% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9D659-1