GITR Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-997-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
AITR,GITR,TNFRSF18,CD357
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Background References:
- Gurney A.L., et al., 1999, Curr. Biol. 9:215-218.
- Park MS., et al., 2007, Yonsei Med J 48 (5): 839-46.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Official Name:
16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130084C11 product:tumor necrosis factor receptor superfamily, member 18, full insert sequence
NCBI Official Symbol:
GITR
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Predicted Molecular Weight:
15.2 kDa
Protein Accession #:
Q8C4K3
Purity:
>95% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q8C4K3