ProSci

B18R Recombinant Protein

Product Code:
 
PSI-97-072
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Vaccinia Virus
Application:
 
Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-97-072-0.05mg0.05mg£867.00
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Further Information

Additional Names:
B18R
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
B18R is a type I interferon (IFN)-binding protein and it is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus, which contains two Ig-like C2-type domains and one Ig-like V-type domain. B18R exists in a soluble and a membrane-bound form. As a type I IFN receptor, B18R counteracts the antiviral effects of host IFN-alpha/beta. Also, B18R acts as a soluble IFN-alpha receptor and thus inhibits the interaction between host IFN-alpha and its receptor.
Background References:
  • Alcami A., et al., 2000, J. Virol. 74:11230-11239.
  • Waibler Z., et al., 2009, J. Virol. 83:1563-1571.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
3707577
NCBI Official Name:
Soluble interferon alpha/beta receptor B18
NCBI Official Symbol:
B18R
NCBI Organism:
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Physical State:
Lyophilized
Predicted Molecular Weight:
40.3 kDa
Protein Accession #:
P25213
Purity:
>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P25213

Documents