ANGPTL7 Recombinant Protein
Code | Size | Price |
---|
PSI-96-822-0.1mg | 0.1mg | £801.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
ANGPTL7,CDT6
Application Note:
This recombinant protein can be used for E, WB. For research use only.
Background:
Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.
Background References:
- Peek R., et al., 1998, Invest. Opthalmol. Visual Sci. 39 (10): 1782-1788.
- Peek R., et al., 2002, J. Biol. Chem. 277 (1): 686-693.
- Kuchtey, J. et al., 2008, Invest. Opthalmol. Visual Sci. 49 (8): 3438-3448.
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human ANGPTL7, His Tag at 5 ug/mL (100 uL/well) can bind Human LILRB4, Fc Tag with a linear range of 0.031-0.5 ug/mL (Routinely tested).
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
10218
NCBI Official Name:
angiopoietin-related protein 7 precursor
NCBI Official Symbol:
ANGPTL7
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
39 kDa
Protein Accession #:
O43827-1
Purity:
>85% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
O43827-1