BAFFR Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-828-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
BAFFR,TNFRSF13C,BAFF-R,BROMIX,CD268,CVID4,prolixin
Application Note:
This recombinant protein can be used for E, WB. For research use only.
Background:
BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
Background References:
- Thompson JS., et al.,2001, Science, 293 (5537): 2108-2111.
- Mbrose CM., 2003, Journal of Biological Regulators and Homeostatic Agents, 16 (3): 211-213.
- Treml LS., et al., 2006, Seminars in Immunology, 18 (5): 297-304.
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human BAFF, His Tag at 5 ug/mL (100 uL/well) can bind Human BAFFR, Fc Tag with a linear range of 2-31 ng/mL.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
Fc Tag
NCBI Gene ID #:
115650
NCBI Official Name:
tumor necrosis factor receptor superfamily member 13C
NCBI Official Symbol:
BAFFR
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
33.2 kDa
Protein Accession #:
Q96RJ3-1
Purity:
>95% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q96RJ3-1